INTRACTABLE COUGH DUE TO ENDOBRONCHIAL CHONDROMA

Intractable cough due to endobronchial chondroma

A 62-year-old man, suffering from bronchial asthma was evaluated due to intractable cough.His dyspnea was controlled but Heart Token cough remained unresponsive to escalation of asthma management steps.Cough occurred in bouts, especially during night time and was occasionally productive of mucoid sputum.Other than bilateral rhonchi on chest auscult

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Quantifying the Matrix Metalloproteinase 2 (MMP2) Spatially in Tissues by Probe via MALDI Imaging Mass Spectrometry

As a matrix metalloproteinase, the abnormal expression of MMP2 is associated with multiple biological processes, including tissue remodeling and cancer progression.Therefore, spatial analysis of MMP2 protein in tissues can be used as an important approach to evaluate the expression distribution of MMP2 in complex tissue environments, which will hel

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Caenorhabditis elegans organic cation transporter-2 is a novel drug uptake transporter that mediates induced mutagenesis by environmental genotoxic compounds

Uptake transporters are being studied for roles in the entry of therapeutic drugs into cells and thus can be exploited to improve the treatment of various diseases.The Moisturizer live whole model organism, Caenorhabditis elegans, offers an array of advantages to investigate the roles of these transporters.This organism possesses two organic cation

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Transcutaneous Spinal Cord Direct-Current Stimulation Modulates Functional Activity and Integration in Idiopathic Restless Legs Syndrome

Idiopathic restless legs syndrome (RLS) is a sensorimotor disorder and is suggested to be caused by central nervous system abnormalities.Non-invasive transcutaneous spinal direct-current stimulation (tsDCS) was recently used for RLS therapy.However, the neurophysiological basis of tsDCS HERBATINT 4C treatment is still unknown.In this study, we expl

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A stochastic rupture earthquake code based on the fiber bundle model (TREMOL v0.1): application to Mexican subduction earthquakes

In general terms, earthquakes are the result of brittle failure within the heterogeneous crust of the Earth.However, the rupture process of a heterogeneous material is a complex physical problem that is difficult to model deterministically due to numerous parameters and physical conditions, which are largely unknown.Considering the variability with

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